Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | UGCG | Q16739 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209033 | 0.86 | GPR52 (0.47) | GPR52MEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL3215806 | 0.85 | GPR52 (0.50) | GPR52RAB9A | |
| SCHEMBL3206663 | 0.85 | GPR52 (0.68) | GPR52ALDH1A1 | |
| SCHEMBL3209846 | 0.85 | GPR52 (0.69) | GPR52HTTALDH1A1 | |
| SCHEMBL3221889 | 0.84 | GPR52 (0.71) | GPR52ALDH1A1 | |
| SCHEMBL1847987 | 0.82 | GPR52 (0.48) | MAPTGPR52MEN1RAB9AKMT2A | |
| SCHEMBL1847685 | 0.82 | GPR52 (0.47) | GPR52MEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1851681 | 0.81 | GPR52 (0.67) | GPR52ALDH1A1 | |
| SCHEMBL1850454 | 0.79 | MAPT (0.52) | MAPTGPR52MEN1HTTRAB9A | |
| SCHEMBL1851677 | 0.78 | GPR52 (0.62) | GPR52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |