Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215806 | 0.96 | GPR52 (0.50) | GPR52S1PR4S1PR5DHODHAKR1C3 | |
| SCHEMBL3209033 | 0.95 | GPR52 (0.47) | GPR52S1PR4S1PR5RXRARXRB | |
| SCHEMBL1847676 | 0.88 | GPR52 (0.44) | GPR52S1PR4S1PR5ALDH1A1AKR1C3 | |
| SCHEMBL1851681 | 0.84 | GPR52 (0.67) | GPR52S1PR4S1PR5ALDH1A1 | |
| SCHEMBL3209846 | 0.84 | GPR52 (0.69) | GPR52S1PR4S1PR5ALDH1A1 | |
| SCHEMBL1847987 | 0.83 | GPR52 (0.48) | GPR52S1PR4S1PR5ALDH1A1MEN1 | |
| SCHEMBL1847683 | 0.82 | MAPT (0.50) | GPR52ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL3206663 | 0.81 | GPR52 (0.68) | GPR52S1PR4S1PR5ALDH1A1 | |
| SCHEMBL3221889 | 0.79 | GPR52 (0.71) | GPR52S1PR4S1PR5ALDH1A1 | |
| SCHEMBL1850455 | 0.79 | GPR52 (0.49) | GPR52S1PR4S1PR5DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |