Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995615 | 0.84 | LOXL2 (0.57) | LOXL2KIF11ALKBH3PCSK9DAO | |
| SCHEMBL7419729 | 0.81 | LOXL2 (0.57) | LOXL2PCSK9DAORAB9ANPC1 | |
| SCHEMBL6994727 | 0.81 | LOXL2 (0.57) | LOXL2ALKBH3PCSK9DAORAB9A | |
| SCHEMBL6992353 | 0.81 | LOXL2 (0.49) | LOXL2KIF11PCSK9KDM5AKDM4C | |
| SCHEMBL17027129 | 0.79 | F2 (0.55) | KIF11ALKBH3DAOKDM5AKDM4C | |
| SCHEMBL865051 | 0.79 | LOXL2 (0.72) | LOXL2PCSK9DAORAB9ANPC1 | |
| SCHEMBL18440586 | 0.79 | SRD5A2 (0.55) | KDM5AKDM4CKDM5BF2 | |
| SCHEMBL18440581 | 0.78 | HRH3 (0.48) | RAB9ANPC1F2HSP90AA1KDM4E | |
| SCHEMBL6990096 | 0.77 | KIF11 (0.49) | KIF11KDM5AKDM4CKDM5BKDM4E | |
| SCHEMBL19360375 | 0.77 | KDM4E (0.46) | KIF11RAB9ANPC1KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024018-A1 | MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, INC. (US) | 2017-02-09 | — | — | WO | disclosed |