Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18447717 | 0.82 | CYP11B2 (0.39) | CYP11B2GABRG2GABRB3GABRA5BRPF1 | |
| SCHEMBL18485086 | 0.78 | KDM4E (0.39) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL18479999 | 0.77 | CHKA (0.37) | GABRG2GABRB3GABRA5GABRA1GABRA6 | |
| SCHEMBL18477081 | 0.76 | GABRG2 (0.38) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL20463563 | 0.75 | CYP11B2 (0.38) | CYP11B2GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL18483132 | 0.75 | CYP11B2 (0.41) | CYP11B2GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL18476349 | 0.74 | CSNK1D (0.40) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL18482579 | 0.74 | GPR119 (0.41) | GABRG2GABRB3GABRA5GABRA1GABRA2 | |
| SCHEMBL18486749 | 0.73 | CHRM2 (0.39) | GPR119HTTALDH1A1LMNA | |
| SCHEMBL18441912 | 0.72 | CYP11B2 (0.39) | CYP11B2GABRG2GABRB3GABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024025-A1 | 3-(1H-PYRROLO[2,3-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | KC SUNIL KUMAR (US) | 2017-02-09 | — | — | WO | disclosed |
| WO-2017023981-A1 | 3-(1H-PYRROLO[2,3-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | disclosed |
| WO-2017023975-A1 | 3-(1H-PYRROLO[2,3-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | disclosed |