Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948696 | 0.84 | KMT2A (0.51) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12722664 | 0.83 | ALDH1A1 (0.50) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12722614 | 0.83 | ALDH1A1 (0.50) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5338500 | 0.83 | ALDH1A1 (0.50) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL6307871 | 0.82 | ALDH1A1 (0.49) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL15358250 | 0.81 | KMT2A (0.52) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4578508 | 0.79 | KMT2A (0.58) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22710505 | 0.79 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1GAAEPHX1 | |
| SCHEMBL23295438 | 0.78 | ITGB3 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23295439 | 0.78 | ITGB3 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567304-B2 | Quinazolinedione derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2017-02-14 | — | — | US | disclosed |