Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25502064 | 0.92 | GLA (0.53) | KMT2AGLACHRNB2CHRNA4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL25205278 | 0.90 | GLA (0.52) | KMT2AGLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL17726560 | 0.86 | HTR2C (0.55) | KMT2AGLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL20224979 | 0.85 | KMT2A (0.56) | KMT2AGLACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL305021 | 0.84 | ALDH1A1 (0.56) | KMT2AGLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL18477758 | 0.84 | KMT2A (0.46) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7354989 | 0.83 | GLA (0.56) | KMT2AGLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL304920 | 0.83 | NPC1 (0.55) | KMT2AGLAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24988336 | 0.83 | CHRNB2 (0.58) | KMT2ACHRNB2CHRNA4CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL4072243 | 0.82 | GLA (0.54) | KMT2AGLAALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |