Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18482878 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL18471452 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL1232645 | 0.73 | KDM4E (0.45) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL3469899 | 0.73 | KDM4E (0.42) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL2117930 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL2115936 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL30702649 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL197196 | 0.70 | PCSK9 (0.60) | ALDH1A1KDM4EGAAHSD17B10CYP2A6 | |
| SCHEMBL12133854 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAHSD17B10MAPK1 | |
| SCHEMBL4023346 | 0.68 | ESR1 (0.41) | ALDH1A1KDM4EGAAHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10186667-B2 | Diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid compounds and organic light emitting device comprising the same | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2019-01-22 | — | — | US | disclosed |
| US-20170040548-A1 | DIPHENYLIMIDAZOLE-FUSED, SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10186667-B2 | Diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid compounds and organic light emitting device comprising the same | SLCO4C1, SLCO2B1, SLCO1B1 | ALDH1A1 1491/4885KDM4E 4755/4885GAA 2743/4885 |
| US-20170040548-A1 | DIPHENYLIMIDAZOLE-FUSED, SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | SLCO4C1, SLCO2B1, SLCO1B1 | ALDH1A1 1491/4885KDM4E 4755/4885GAA 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.