SCHEMBL3469899

SCHEMBL3469899

Cn1cccc1-c1nc(Cl)nc(Cl)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.42
ALDH1A1 P00352 4/20 0.42
GAA P10253 1/20 0.42
CYP2A6 P11509 1/20 0.42
CYP2A13 Q16696 1/20 0.42
NPC1 O15118 2/20 0.41
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PCSK9 Q8NBP7 1/20 0.39
HSD17B10 Q99714 2/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 2/20 0.35
ALOX15 P16050 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2117930 0.82 ALDH1A1 (0.41) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL18482878 0.78 ALDH1A1 (0.47) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL1232645 0.76 KDM4E (0.45) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL2115936 0.74 ALDH1A1 (0.41) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL29094518 0.74 ALOX15 (0.41) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL18483370 0.73 ALDH1A1 (0.40) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL18471452 0.73 ALDH1A1 (0.40) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL197196 0.72 PCSK9 (0.60) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL30702649 0.69 ALDH1A1 (0.47) KDM4EALDH1A1GAACYP2A6CYP2A13
SCHEMBL29094509 0.69 ALDH1A1 (0.44) KDM4EALDH1A1GAACYP2A6CYP2A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed
EP-1380583-B1 Bis-resorcinol-triazines and their use as sunscreen agents CIBA HOLDING INC (CH) 2009-07-01 EP disclosed
EP-1380583-A2 Bis-resorcinol-triazines and their use as sunscreen agents Ciba Specialty Chemicals Holding Inc. (CH) 2004-01-14 EP disclosed
US-5955060-A COSMETICS AND VETERINARY MEDICINE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-21 US disclosed
EP-0775698-A1 Bis-resorcinol-triazines as UV absorber triazine Ciba SC Holding AG (CH) 1997-05-28 EP disclosed
EP-0258391-A1 USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD RHONE POULENC NEDERLAND B.V. (NL) 1988-03-09 EP disclosed
WO-1987004321-A2 USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD RHONE-POULENC NEDERLANDS B.V. (NL) 1987-07-30 WO disclosed