Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 18/20 | 0.65 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850259 | 0.83 | GPR52 (0.61) | GPR52S1PR4S1PR5 | |
| SCHEMBL3209079 | 0.81 | GPR52 (0.70) | GPR52S1PR4S1PR5 | |
| SCHEMBL1849010 | 0.80 | GPR52 (0.54) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL1851112 | 0.79 | GPR52 (1.00) | GPR52 | |
| SCHEMBL3209848 | 0.79 | GPR52 (0.66) | GPR52S1PR4S1PR5 | |
| SCHEMBL1861066 | 0.76 | GPR52 (0.64) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL3218871 | 0.74 | GPR52 (0.71) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL3212807 | 0.74 | GPR52 (0.74) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL3206663 | 0.73 | GPR52 (0.68) | GPR52S1PR4S1PR5 | |
| SCHEMBL3221109 | 0.73 | GPR52 (0.72) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |