Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 17/20 | 0.61 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209079 | 0.93 | GPR52 (0.70) | GPR52SCDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL1861066 | 0.93 | GPR52 (0.64) | GPR52SCDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL1851846 | 0.87 | GPR52 (0.45) | GPR52SCDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL1850452 | 0.86 | GPR52 (0.46) | GPR52SCDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL3218871 | 0.86 | GPR52 (0.71) | GPR52SCDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL3209848 | 0.84 | GPR52 (0.66) | GPR52S1PR4S1PR5ALDH1A1POLB | |
| SCHEMBL1848384 | 0.83 | GPR52 (0.65) | GPR52S1PR4S1PR5 | |
| SCHEMBL3198211 | 0.82 | GPR52 (0.70) | GPR52SCDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL3204669 | 0.81 | GPR52 (0.49) | GPR52SCDS1PR4S1PR5ALDH1A1 | |
| SCHEMBL1849541 | 0.80 | GPR52 (0.66) | GPR52SCDS1PR4S1PR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |