Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198656 | 0.84 | GPR52 (0.49) | GPR52S1PR4S1PR5KDM4EMEN1 | |
| SCHEMBL1853402 | 0.83 | GPR52 (0.75) | GPR52S1PR4S1PR5NR4A2 | |
| SCHEMBL1847713 | 0.82 | GPR52 (0.62) | GPR52S1PR4S1PR5NR4A2MRGPRX4 | |
| SCHEMBL1849012 | 0.82 | GPR52 (0.53) | GPR52S1PR4S1PR5KDM4EMEN1 | |
| SCHEMBL3206554 | 0.81 | GPR52 (0.46) | GPR52S1PR4S1PR5KDM4EMEN1 | |
| SCHEMBL1848384 | 0.80 | GPR52 (0.65) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL1850455 | 0.80 | GPR52 (0.49) | GPR52S1PR4S1PR5KDM4EMEN1 | |
| SCHEMBL1853719 | 0.77 | GPR52 (0.44) | GPR52S1PR4S1PR5KDM4EMEN1 | |
| SCHEMBL1852737 | 0.77 | HTR2A (0.45) | USP2CYP3A4NR1I2ADRB1HTR1A | |
| SCHEMBL1849541 | 0.77 | GPR52 (0.66) | GPR52S1PR4S1PR5MRGPRX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |