SCHEMBL18485459

SCHEMBL18485459

C=CCOC(=O)N1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.51
NPSR1 Q6W5P4 2/20 0.49
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP1A2 P05177 1/20 0.47
MAPT P10636 1/20 0.47
AKR1B1 P15121 1/20 0.47
ALOX15 P16050 1/20 0.47
ERCC1 P07992 1/20 0.46
FEN1 P39748 1/20 0.46
ERCC4 Q92889 1/20 0.46
HEXA P06865 2/20 0.44
HEXB P07686 2/20 0.44
CYP1B1 Q16678 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10768629 0.86 NPSR1 (0.63) FGFR1NPSR1ALDH1A1HSD17B10MAPT
SCHEMBL18485418 0.82 ALDH1A1 (0.56) FGFR1MEN1KMT2AALDH1A1KDM4E
SCHEMBL18485429 0.78 TDP1 (0.55) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL18485457 0.78 NPSR1 (0.44) FGFR1NPSR1MEN1KMT2AALDH1A1
SCHEMBL25583410 0.77 CTRB1 (0.60) NPSR1MEN1KMT2AALDH1A1KDM4E
SCHEMBL8677467 0.76 ALDH1A1 (0.73) FGFR1NPSR1MEN1KMT2AALDH1A1
SCHEMBL6345866 0.76 KDM4E (0.49) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL18485439 0.75 ALDH1A1 (0.59) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL18485464 0.73 KDM4E (0.51) NPSR1MEN1KMT2AALDH1A1KDM4E
SCHEMBL28108470 0.72 ALDH1A1 (0.51) MEN1KMT2AALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170117588-A1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2017-04-27 US disclosed
EP-3131153-A1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS ELECTROLYTE, AND POWER STORAGE DEVICE Sumitomo Seika Chemicals Co., Ltd. (JP) 2017-02-15 EP disclosed
CN-106133984-A Addition agent of non-aqueous electrolyte, nonaqueous electrolytic solution and electrical storage device 住友精化株式会社 2016-11-16 CN disclosed