SCHEMBL6345866

SCHEMBL6345866

C=C(C)C(=O)OCCOC(=O)N1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 2/20 0.43
CYP1A2 P05177 1/20 0.43
AKR1B1 P15121 1/20 0.43
ALOX15 P16050 1/20 0.43
CYP1B1 Q16678 1/20 0.42
ERCC1 P07992 1/20 0.42
FEN1 P39748 1/20 0.42
ERCC4 Q92889 1/20 0.42
RXFP1 Q9HBX9 1/20 0.41
HEXA P06865 3/20 0.40
HEXB P07686 3/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6346833 0.83 HEXA (0.55) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL18485429 0.82 TDP1 (0.55) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL13609715 0.81 RXFP1 (0.61) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL18485418 0.81 ALDH1A1 (0.56) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL6349229 0.80 KDM4E (0.44) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL24756847 0.77 KDM4E (0.52) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL24756852 0.77 KDM4E (0.49) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL18485459 0.76 FGFR1 (0.51) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL13898970 0.75 KDM4E (0.57) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL24634086 0.75 RAB9A (0.56) KDM4EALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975160-B1 Polymerizable compound, polymer, ink composition, printed articles and inkjet recording method FUJIFILM CORP (JP) 2013-01-16 EP disclosed
US-8173226-B2 Polymerizable compound , polyethylene glycol mono(meth)acrylate, a polystyrene oligomer having a methacryloyl group at one terminal, acrylic macromonomer imides FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-20090214797-A1 INKJET INK COMPOSITION, AND INKJET RECORDING METHOD AND PRINTED MATERIAL EMPLOYING SAME FUJIFILM CORPORATION (JP) 2009-08-27 US disclosed
US-20090214797-A1 INKJET INK COMPOSITION, AND INKJET RECORDING METHOD AND PRINTED MATERIAL EMPLOYING SAME FUJIFILM CORPORATION (JP) 2009-08-27 US disclosed
US-20080241416-A1 POLYMERIZABLE COMPOUND, POLYMER, INK COMPOSITION, PRINTED ARTICLES AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080241416-A1 POLYMERIZABLE COMPOUND, POLYMER, INK COMPOSITION, PRINTED ARTICLES AND INKJET RECORDING METHOD CNOT1, CCNT1, SCO2 KDM4E 930/4885ALDH1A1 1750/4885MEN1 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.