Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 12/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | BLVRB | P30043 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849223 | 0.92 | GPR52 (0.55) | GPR52S1PR5S1PR4 | |
| SCHEMBL1850277 | 0.88 | GPR52 (0.54) | GPR52S1PR5S1PR4 | |
| SCHEMBL1851499 | 0.86 | GPR52 (0.65) | GPR52S1PR5S1PR4 | |
| SCHEMBL1849572 | 0.84 | GPR52 (0.71) | GPR52S1PR5PTGER1S1PR4MAOA | |
| SCHEMBL1852578 | 0.83 | GPR52 (0.61) | GPR52S1PR5S1PR4 | |
| SCHEMBL1848035 | 0.79 | GPR52 (0.53) | GPR52S1PR5S1PR4MAOABLVRB | |
| SCHEMBL1850479 | 0.78 | GPR52 (0.53) | GPR52PTGER1 | |
| SCHEMBL1850213 | 0.78 | GPR52 (0.54) | GPR52S1PR5PTGER1S1PR4 | |
| SCHEMBL1848226 | 0.78 | GPR52 (0.42) | GPR52PTGER1HDAC6 | |
| SCHEMBL1851248 | 0.77 | GPR52 (0.51) | GPR52S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |