Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851664 | 0.88 | GPR52 (0.51) | GPR52ALDH1A1CA2 | |
| SCHEMBL1852822 | 0.86 | GPR52 (0.73) | GPR52ALDH1A1GAAHSD17B10PARP1 | |
| SCHEMBL1848566 | 0.85 | GPR52 (0.59) | GPR52ALDH1A1GAAHSD17B10 | |
| SCHEMBL3213715 | 0.85 | GPR52 (0.56) | GPR52PLA2G2APTGER1AKR1C3AKR1C2 | |
| SCHEMBL1848214 | 0.82 | GPR52 (0.74) | GPR52PLA2G2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL1849783 | 0.79 | GPR52 (0.56) | GPR52PLA2G2APTGER1AKR1C3AKR1C2 | |
| SCHEMBL1850572 | 0.79 | GPR52 (0.74) | GPR52PLA2G2A | |
| SCHEMBL1847069 | 0.78 | GPR52 (0.36) | GPR52ALDH1A1GAAHSD17B10PARP1 | |
| SCHEMBL1848607 | 0.78 | GPR52 (0.56) | GPR52PTGER1 | |
| SCHEMBL3208322 | 0.77 | GPR52 (0.49) | GPR52PLA2G2APTGER1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |