Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 9/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850065 | 0.91 | GPR52 (0.64) | GPR52S1PR5S1PR4 | |
| SCHEMBL1853402 | 0.89 | GPR52 (0.75) | GPR52S1PR5S1PR4 | |
| SCHEMBL1849090 | 0.87 | GPR52 (0.60) | GPR52S1PR5S1PR4 | |
| SCHEMBL1849572 | 0.86 | GPR52 (0.71) | GPR52S1PR5S1PR4 | |
| SCHEMBL3219334 | 0.86 | GPR52 (0.82) | GPR52S1PR5S1PR4 | |
| SCHEMBL3198362 | 0.85 | GPR52 (0.61) | GPR52S1PR5S1PR4 | |
| SCHEMBL1849113 | 0.84 | GPR52 (0.63) | GPR52S1PR5S1PR4 | |
| SCHEMBL3209014 | 0.84 | GPR52 (0.83) | GPR52S1PR5S1PR4 | |
| SCHEMBL1848607 | 0.83 | GPR52 (0.56) | GPR52S1PR5S1PR4 | |
| SCHEMBL1847713 | 0.82 | GPR52 (0.62) | GPR52S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |