Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 4/20 | 0.73 |
| ▸ | TK2 | O00142 | 2/20 | 0.57 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16871787 | 0.93 | P2RY2 (0.75) | P2RY2TK2DNPH1IMPDH2P2RY6 | |
| SCHEMBL17369140 | 0.93 | P2RY2 (0.75) | P2RY2TK2DNPH1IMPDH2P2RY6 | |
| SCHEMBL16871721 | 0.83 | P2RY2 (0.54) | P2RY2TK2IMPDH2P2RY6P2RY12 | |
| SCHEMBL21465066 | 0.81 | TK2 (0.72) | P2RY2TK2DNPH1P2RY6P2RY14 | |
| SCHEMBL21465110 | 0.81 | TK2 (0.72) | P2RY2TK2DNPH1P2RY6P2RY14 | |
| SCHEMBL4959499 | 0.81 | TK2 (0.72) | P2RY2TK2DNPH1P2RY6P2RY14 | |
| SCHEMBL7040216 | 0.79 | DNPH1 (0.68) | P2RY2TK2DNPH1P2RY6P2RY14 | |
| SCHEMBL17363852 | 0.78 | DNPH1 (0.63) | DNPH1P2RY6P2RY14NT5E | |
| SCHEMBL16871723 | 0.78 | P2RY2 (0.56) | P2RY2TK2DNPH1IMPDH2P2RY12 | |
| SCHEMBL14948888 | 0.77 | TK2 (0.54) | P2RY2TK2DNPH1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130597-B1 | OLIGONUCLEOTIDE HAVING A NON-NATURAL NUCLEOTIDE AT THE 5'-TERMINAL | KYOWA KIRIN CO LTD (JP) | 2021-11-10 | — | — | EP | disclosed |
| US-10342819-B2 | Oligonucleotide having non-natural nucleotide at 5′-terminal thereof | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20170354673-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-14 | — | — | US | disclosed |
| EP-3130597-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | Kyowa Hakko Kirin Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342819-B2 | Oligonucleotide having non-natural nucleotide at 5′-terminal thereof | RNGTT, UPF1, NSUN3 | P2RY2 2497/4885TK2 580/4885DNPH1 2051/4885 |
| US-20170354673-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | RNGTT, UPF1, NSUN3 | P2RY2 2562/4885TK2 592/4885DNPH1 2035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.