SCHEMBL18486707

SCHEMBL18486707

CCOP(=O)(c1ccccc1)c1ccccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
ACHE P22303 1/20 0.46
AOX1 Q06278 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 5/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
LMNA P02545 2/20 0.41
RECQL P46063 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CA2 P00918 2/20 0.41
KCNH2 Q12809 1/20 0.41
HDAC1 Q13547 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL563394 0.82 KMT2A (0.70) KMT2AMEN1ACHEAOX1NPSR1
SCHEMBL18486552 0.81 ALDH1A1 (0.44) KMT2AMEN1ALDH1A1LMNARECQL
SCHEMBL28890291 0.80 ALDH1A1 (0.47) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL29468650 0.80 KMT2A (0.50) KMT2AMEN1ACHEAOX1NPSR1
SCHEMBL779596 0.80 KMT2A (0.50) KMT2AMEN1ACHEAOX1NPSR1
Hydrogen Peroxide SCHEMBL8527170 0.80 KMT2A (0.68) KMT2AMEN1ACHEAOX1NPSR1
SCHEMBL641441 0.79 MEN1 (0.53) KMT2AMEN1ACHEAOX1NPSR1
SCHEMBL10960177 0.77 NPSR1 (0.42) KMT2AMEN1ACHEAOX1NPSR1
SCHEMBL10960102 0.76 AOX1 (0.41) KMT2AMEN1ACHEAOX1NPSR1
SCHEMBL10688055 0.74 ALDH1A1 (0.43) KMT2AMEN1NPSR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10103401-B2 Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same TORAY INDUSTRIES, INC. (JP) 2018-10-16 US disclosed
EP-3131145-B1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME TORAY INDUSTRIES (JP) 2018-09-05 EP disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
EP-3131145-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME Toray Industries, Inc. (JP) 2017-02-15 EP disclosed