SCHEMBL28890291

SCHEMBL28890291

NOP(=O)(c1ccccc1)c1ccccc1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 2/20 0.43
RECQL P46063 1/20 0.43
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CA2 P00918 2/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
CFTR P13569 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18486552 0.85 ALDH1A1 (0.44) ALDH1A1L3MBTL1LMNARECQLMEN1
SCHEMBL276503 0.83 ALDH1A1 (0.58) ALDH1A1L3MBTL1LMNARECQLMEN1
Iodide SCHEMBL15313341 0.81 ALDH1A1 (0.56) ALDH1A1L3MBTL1LMNARECQLMEN1
SCHEMBL18486707 0.80 KMT2A (0.50) ALDH1A1L3MBTL1LMNARECQLMEN1
Iodide SCHEMBL15313340 0.79 ALDH1A1 (0.54) ALDH1A1L3MBTL1LMNARECQLMEN1
SCHEMBL31207462 0.77 ALDH1A1 (0.44) ALDH1A1L3MBTL1LMNARECQLMEN1
SCHEMBL7640122 0.77 ALDH1A1 (0.44) ALDH1A1L3MBTL1LMNARECQLMEN1
SCHEMBL10688055 0.77 ALDH1A1 (0.43) ALDH1A1L3MBTL1LMNARECQLMEN1
SCHEMBL18037934 0.73 CA2 (0.48) ALDH1A1LMNARECQLMEN1KMT2A
SCHEMBL3071689 0.71 CYP3A4 (0.47) ALDH1A1L3MBTL1LMNARECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291010-B Epoxy resin composition, prepreg, and fiber-reinforced composite material 东丽株式会社 2020-05-08 CN disclosed