Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24170586 | 1.00 | THRB (0.35) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL22072464 | 0.96 | AAK1 (0.33) | THRBAAK1POLBDGAT1S1PR1 | |
| SCHEMBL18476361 | 0.95 | ELANE (0.36) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL22592280 | 0.93 | ELANE (0.36) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL15180382 | 0.92 | THRB (0.40) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL16559841 | 0.91 | THRB (0.39) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL25933524 | 0.91 | L3MBTL1 (0.34) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL26000349 | 0.91 | THRB (0.35) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL21400842 | 0.90 | THRB (0.40) | THRBAAK1POLBAPEX1HTT | |
| SCHEMBL16559823 | 0.90 | THRB (0.40) | THRBAAK1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295511-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-09-21 | — | — | US | disclosed |
| US-20190241809-A1 | COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2019-08-08 | — | — | US | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-20170037315-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241809-A1 | COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA | NEFM, MDN1, VCL | THRB 4061/4885AAK1 2133/4885POLB 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.