Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18487745 | 0.84 | DYRK1A (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL18487739 | 0.81 | DYRK1A (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL18487536 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1181326 | 0.69 | KDM4E (0.79) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29670412 | 0.69 | KDM4E (0.79) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL532262 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29562964 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL30115280 | 0.69 | KDM4E (0.79) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29643258 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| 7-Methoxy-3-Methylcarbazole SCHEMBL31214611 | 0.68 | KDM4E (0.67) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023916-A1 | SMALL MOLECULE ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2017-02-09 | — | — | WO | disclosed |