Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853528 | 0.97 | GPR52 (0.51) | GPR52SCD | |
| SCHEMBL3219563 | 0.88 | GPR52 (0.55) | GPR52SCD | |
| SCHEMBL3209653 | 0.87 | GPR52 (0.62) | GPR52SCD | |
| SCHEMBL1854179 | 0.86 | GPR52 (0.62) | GPR52SCD | |
| SCHEMBL13506065 | 0.84 | GPR52 (0.51) | GPR52SCD | |
| SCHEMBL1849247 | 0.84 | GPR52 (0.60) | GPR52SCD | |
| SCHEMBL1850092 | 0.84 | GPR52 (0.59) | GPR52SCD | |
| SCHEMBL1853257 | 0.84 | GPR52 (0.55) | GPR52 | |
| SCHEMBL1848119 | 0.84 | GPR52 (0.71) | GPR52 | |
| SCHEMBL1863284 | 0.83 | GPR52 (0.59) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885SCD 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.