Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 14/20 | 0.55 |
| ▸ | SCD | O00767 | 3/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850092 | 0.95 | GPR52 (0.59) | GPR52SCD | |
| SCHEMBL1853528 | 0.92 | GPR52 (0.51) | GPR52SCD | |
| SCHEMBL3209653 | 0.91 | GPR52 (0.62) | GPR52SCD | |
| SCHEMBL1855306 | 0.91 | GPR52 (0.69) | GPR52 | |
| SCHEMBL3263212 | 0.90 | GPR52 (0.69) | GPR52SCD | |
| SCHEMBL1849417 | 0.88 | GPR52 (0.53) | GPR52SCD | |
| SCHEMBL3208972 | 0.87 | GPR52 (0.73) | GPR52 | |
| SCHEMBL1852635 | 0.86 | GPR52 (0.57) | GPR52NR4A2S1PR4S1PR5 | |
| SCHEMBL3206560 | 0.86 | GPR52 (0.73) | GPR52SCD | |
| SCHEMBL1853172 | 0.85 | GPR52 (0.67) | GPR52NR4A2S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885SCD 3465/4885NR4A2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.