Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 5/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20279382 | 0.91 | HSD11B1 (0.47) | HSD11B1HSD11B2ACHENR1H4CES2 | |
| SCHEMBL20284781 | 0.91 | HSD11B1 (0.47) | HSD11B1HSD11B2ACHENR1H4CES2 | |
| SCHEMBL29843558 | 0.81 | HSD11B1 (0.43) | HSD11B1HSD11B2ACHENR1H4CES2 | |
| SCHEMBL5824299 | 0.78 | HSD11B1 (0.61) | HSD11B1HSD11B2ACHENR1H4CES2 | |
| SCHEMBL4232501 | 0.73 | HSD11B1 (0.62) | HSD11B1HSD11B2ACHEFNTAFNTB | |
| SCHEMBL4232495 | 0.73 | HSD11B1 (0.62) | HSD11B1HSD11B2ACHEFNTAFNTB | |
| Argentatine A SCHEMBL18495437 | 0.70 | TYR (0.48) | HSD11B1NR1H4CES2 | |
| Argentatine A SCHEMBL20888305 | 0.70 | TYR (0.48) | HSD11B1NR1H4CES2 | |
| Argentatine A SCHEMBL18495439 | 0.70 | TYR (0.48) | HSD11B1NR1H4CES2 | |
| Argentatine A SCHEMBL20279380 | 0.70 | TYR (0.48) | HSD11B1NR1H4CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328874-B1 | METHOD FOR THE SEPARATION OF THE ISOPRENIC CONSTITUENTS OF GUAYULE | VERSALIS SPA (IT) | 2019-11-06 | — | — | EP | disclosed |
| WO-2017021852-A1 | METHOD FOR THE SEPARATION OF THE ISOPRENIC CONSTITUENTS OF GUAYULE | VERSALIS S.P.A. (IT) | 2017-02-09 | — | — | WO | disclosed |