SCHEMBL29843558

SCHEMBL29843558

CC(CC(O)C(C)(O)C(C)C)[C@H]1[C@@H](O)C[C@@]2(C)[C@@H]3CC[C@H]4C(C)(C)C(=O)CC[C@@]45C[C@@]35CC[C@]12C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 3/20 0.43
▸ CDC25B P30305 1/20 0.37
▸ NR1H4 Q96RI1 13/20 0.37
▸ CES2 O00748 6/20 0.37
▸ HSD11B2 P80365 1/20 0.35
▸ ACHE P22303 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20279382 0.86 HSD11B1 (0.47) HSD11B1NR1H4CES2HSD11B2ACHE
SCHEMBL20284781 0.86 HSD11B1 (0.47) HSD11B1NR1H4CES2HSD11B2ACHE
SCHEMBL18495442 0.81 HSD11B1 (0.42) HSD11B1NR1H4CES2HSD11B2ACHE
SCHEMBL5824299 0.72 HSD11B1 (0.61) HSD11B1NR1H4CES2HSD11B2ACHE
SCHEMBL5823474 0.70 HSD11B1 (0.57) HSD11B1CDC25BHSD11B2ACHEMEN1
Argentatine A SCHEMBL18495437 0.69 TYR (0.48) HSD11B1NR1H4CES2
Argentatine A SCHEMBL20279380 0.69 TYR (0.48) HSD11B1NR1H4CES2
Argentatine A SCHEMBL18495439 0.69 TYR (0.48) HSD11B1NR1H4CES2
Argentatine A SCHEMBL20888305 0.69 TYR (0.48) HSD11B1NR1H4CES2
Argentatine A SCHEMBL30836078 0.69 TYR (0.48) HSD11B1NR1H4CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092164-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2025-03-20 — — US disclosed
US-20240059800-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2024-02-22 — — US disclosed
EP-4288443-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2023-12-13 — — EP disclosed
EP-4263567-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2023-10-25 — — EP disclosed
EP-3448951-B1 TIRE SEALANT COMPOSITION BRIDGESTONE CORP (JP) 2022-10-12 — — EP disclosed
WO-2022170364-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2022-08-11 — — WO disclosed
WO-2022133477-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2022-06-23 — — WO disclosed
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