Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.61 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | TOP2A | P11388 | 6/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | CRYAB | P02511 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822876 | 0.88 | HSD11B1 (0.59) | HSD11B1HSD11B2ACHETOP2ATOP2B | |
| SCHEMBL30741399 | 0.85 | HSD11B1 (0.62) | HSD11B1HSD11B2ACHEFNTAFNTB | |
| SCHEMBL20279382 | 0.84 | HSD11B1 (0.47) | HSD11B1HSD11B2ACHETOP2ATOP2B | |
| SCHEMBL20284781 | 0.84 | HSD11B1 (0.47) | HSD11B1HSD11B2ACHETOP2ATOP2B | |
| SCHEMBL31237297 | 0.83 | HSD11B1 (0.82) | HSD11B1ACHETOP2AFNTAFNTB | |
| SCHEMBL5823474 | 0.82 | HSD11B1 (0.57) | HSD11B1HSD11B2ACHEFNTAFNTB | |
| SCHEMBL5824245 | 0.82 | HSD11B1 (0.69) | HSD11B1HSD11B2ACHETOP2AFNTA | |
| Cycloartenone SCHEMBL29504219 | 0.82 | HSD11B1 (0.61) | HSD11B1ACHETOP2AFNTAFNTB | |
| 3Beta,24,25-Trihydroxycycloartane SCHEMBL3306653 | 0.81 | HSD11B1 (0.76) | HSD11B1HSD11B2ACHETOP2ATOP2B | |
| SCHEMBL13642319 | 0.81 | HSD11B1 (0.62) | HSD11B1HSD11B2ACHETOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150004260-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | UNIVERSITY OF MARYLAND, BALTIMORE | 2015-01-01 | — | — | US | disclosed |
| JP-2006131595-A | CARCINOGENESIS PREVENTING AGENT AND METHOD FOR PREPARING CYCLOARTANE-TYPE TRITERPENE COMPOUND | UNIV NIHON | 2006-05-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150004260-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | MAP3K11, MAP3K7, MAP3K1 | HSD11B1 548/4885HSD11B2 644/4885ACHE 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.