SCHEMBL18496

SCHEMBL18496

Cn1nc(-c2noc(=O)[nH]2)cc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
PKM P14618 1/20 0.37
KMO O15229 1/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RARB P10826 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.34
PDE5A O76074 1/20 0.34
PDE1A P54750 1/20 0.34
PDE1B Q01064 1/20 0.34
PDE4D Q08499 1/20 0.34
PDE7A Q13946 1/20 0.34
PDE1C Q14123 1/20 0.34
PDE3A Q14432 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RARG P13631 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18574 0.75 ALDH1A1 (0.41) ALDH1A1PKMGAAL3MBTL1NPC1
SCHEMBL18232 0.72 ALDH1A1 (0.37) ALDH1A1KMORARBRARGPLA2G2A
SCHEMBL15528727 0.72 EPHX2 (0.37) ALDH1A1KMOMAPT
SCHEMBL2339820 0.70 KMO (0.41) KMORARB
SCHEMBL2338992 0.70 RARB (0.37) ALDH1A1KMORARB
SCHEMBL604062 0.70 HPGD (0.37) ALDH1A1KMORARB
SCHEMBL18108 0.69 KMO (0.52) ALDH1A1KMORARBADH5
SCHEMBL603910 0.68 RARB (0.39) ALDH1A1KMORARB
SCHEMBL2338601 0.68 KMO (0.45) ALDH1A1KMORARBNPSR1ADH5
SCHEMBL2331496 0.68 KMO (0.36) ALDH1A1KMORARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025460-A1 OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-03-01 WO disclosed
WO-2012025460-A1 OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-03-01 WO disclosed