SCHEMBL18574

SCHEMBL18574

Cn1nc(-c2noc(=O)n2C)cc1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
PKM P14618 1/20 0.38
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
PTGES2 Q9H7Z7 1/20 0.34
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CMA1 P23946 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALOX15 P16050 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18496 0.75 ALDH1A1 (0.40) ALDH1A1PKMGAAL3MBTL1PTGES2
SCHEMBL15529701 0.74 EPHX2 (0.36) ALDH1A1MAPTNPSR1KMT2ACYP1A2
SCHEMBL18484 0.72 CA2 (0.38) ALDH1A1CMA1MEN1KMT2A
SCHEMBL23664427 0.68 PKM (0.44) ALDH1A1PKMGAAL3MBTL1NPC1
SCHEMBL18577 0.68 IDH1 (0.39) ALDH1A1NPC1POLBRAB9ACMA1
SCHEMBL3436871 0.67 PKM (0.45) ALDH1A1PKMGAANPC1RAB9A
SCHEMBL13471700 0.67 ALDH1A1 (0.60) ALDH1A1PKMGAAL3MBTL1PTGES2
SCHEMBL13098073 0.66 TP53 (0.59) ALDH1A1L3MBTL1NPC1POLBMAPT
SCHEMBL2569391 0.66 ALDH1A1 (0.59) ALDH1A1PKMGAAL3MBTL1PTGES2
SCHEMBL17895138 0.65 PKM (0.44) ALDH1A1PKMGAAL3MBTL1PTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025460-A1 OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-03-01 WO disclosed