Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18000151 | 0.83 | MAPT (0.41) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL18509763 | 0.83 | MAPT (0.41) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31675773 | 0.79 | MAPT (0.43) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL18498550 | 0.72 | MAPT (0.37) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL19872670 | 0.69 | LRRK2 (0.39) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20120047 | 0.69 | PTGS2 (0.36) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18000137 | 0.69 | CRHBP (0.40) | MAPT | |
| SCHEMBL18029101 | 0.69 | CRHBP (0.40) | MAPT | |
| SCHEMBL18000346 | 0.68 | MAPT (0.41) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL26333089 | 0.67 | IKBKB (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016134145-A9 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-02-16 | — | — | WO | claimed |