Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 6/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17382833 | 0.89 | GRM2 (0.44) | RORCAGPAT2PDE2ADDR1GRM2 | |
| SCHEMBL18498926 | 0.88 | AGPAT2 (0.41) | KDM4ETDP1RORCAGPAT2PDE2A | |
| SCHEMBL17967732 | 0.83 | KCNH2 (0.38) | RORCCA12CA1CA2CA9 | |
| SCHEMBL31534718 | 0.83 | KCNH2 (0.38) | RORCCA12CA1CA2CA9 | |
| SCHEMBL18498665 | 0.83 | POLB (0.44) | BACE1DDR1ALOX5APFEN1 | |
| SCHEMBL14678205 | 0.83 | DDR1 (0.42) | RORCAGPAT2PDE2ACA12CA9 | |
| SCHEMBL18498843 | 0.82 | PDE10A (0.38) | RORCAGPAT2PDE2ADDR1 | |
| SCHEMBL18498723 | 0.82 | RORC (0.43) | RORCAGPAT2 | |
| SCHEMBL18819850 | 0.82 | PDE2A (0.41) | RORCAGPAT2PDE2ACA12CA9 | |
| SCHEMBL14684613 | 0.82 | RORC (0.39) | KDM4ETDP1RORCAGPAT2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955472-A | 2- (Hetero) aryl substituted fused heterocyclic derivatives as pesticides | 拜耳作物科学股份公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-02 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-27 | — | — | US | disclosed |
| EP-3331870-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667517-B2 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | KDM4E 2736/4885TDP1 2779/4885RORC 3006/4885 |
| US-20200029567-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | KDM4E 2736/4885TDP1 2779/4885RORC 3006/4885 |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | KDM4E 2736/4885TDP1 2779/4885RORC 3006/4885 |
| US-20180271099-A1 | 2-(Het)aryl-substituted fused heterocycle derivatives as pesticides | CYP1A1, CYP8B1, CYP1B1 | KDM4E 2736/4885TDP1 2779/4885RORC 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.