SCHEMBL18499271

SCHEMBL18499271

C=Cc1ccc(C(=O)OCC2(C)COc3cscc3OC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.36
RARG P13631 2/20 0.36
RASGRP3 Q8IV61 7/20 0.34
PRKCA P17252 7/20 0.34
PRKCE Q02156 5/20 0.34
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
SNCA P37840 1/20 0.33
RARA P10276 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25977827 0.88 SNCA (0.34) RARBRARGRASGRP3PRKCAPRKCE
SCHEMBL25977830 0.83 PRKCA (0.32) RARBRARGRASGRP3PRKCAPRKCE
SCHEMBL23661933 0.76 KDM4E (0.31)
SCHEMBL23661934 0.75 FAAH (0.32) PRKCA
SCHEMBL8776631 0.74 PRKCA (0.38) RASGRP3PRKCAPRKCETAS1R3TAS1R1
SCHEMBL14839397 0.72 ESR1 (0.42)
SCHEMBL28355629 0.72 TSHR (0.43) RASGRP3PRKCAPRKCETAS1R3TAS1R1
SCHEMBL1052411 0.68 CA1 (0.61) TAS1R3TAS1R1
SCHEMBL25439968 0.67 MAPT (0.45)
SCHEMBL21309889 0.67 ALDH1A1 (0.53) RASGRP3PRKCAPRKCEADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10833330-B1 Sulfur composites and polymeric materials from elemental sulfur ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2020-11-10 US disclosed
US-9567439-B1 Sulfur composites and polymeric materials from elemental sulfur THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-02-14 US disclosed
US-9567439-B1 Sulfur composites and polymeric materials from elemental sulfur THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-02-14 US disclosed