Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21668435 | 0.77 | KCNMA1 (0.58) | KCNMA1POLBLMNANPSR1TSHR | |
| SCHEMBL8917812 | 0.77 | KCNMA1 (0.55) | KCNMA1POLBLMNANPSR1TSHR | |
| SCHEMBL80393 | 0.72 | KCNMA1 (1.00) | KCNMA1POLBTSHRSMN1; SMN2RAB9A | |
| SCHEMBL16491892 | 0.68 | KCNMA1 (0.64) | KCNMA1POLBLMNANPSR1TSHR | |
| SCHEMBL4209963 | 0.68 | KCNMA1 (0.64) | KCNMA1POLBLMNATSHRKDM4E | |
| SCHEMBL23840194 | 0.68 | KCNMA1 (0.64) | KCNMA1POLBLMNANPSR1TSHR | |
| SCHEMBL8744193 | 0.68 | KCNMA1 (0.64) | KCNMA1POLBLMNANPSR1TSHR | |
| SCHEMBL25862494 | 0.68 | KCNMA1 (0.64) | KCNMA1POLBLMNANPSR1TSHR | |
| SCHEMBL3969778 | 0.68 | KCNMA1 (0.78) | KCNMA1POLBLMNANPSR1TSHR | |
| SCHEMBL18780221 | 0.68 | KCNMA1 (0.58) | KCNMA1POLBLMNANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566290-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2017-02-14 | — | — | US | disclosed |