SCHEMBL18501167

SCHEMBL18501167

C1CCC(C2CCCN2)NC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
EPAS1 Q99814 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
ALDH1A1 P00352 2/20 0.35
PKM P14618 1/20 0.35
NOS2 P35228 2/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5682444 0.97 L3MBTL1 (0.38) L3MBTL1EPAS1GRIN1GRIN2AALDH1A1
SCHEMBL10622966 0.93 L3MBTL1 (0.36) L3MBTL1EPAS1GRIN1GRIN2AALDH1A1
SCHEMBL29895427 0.93 L3MBTL1 (0.36) L3MBTL1EPAS1GRIN1GRIN2AALDH1A1
SCHEMBL18526481 0.93 ALDH1A1 (0.39) L3MBTL1EPAS1GRIN1GRIN2AALDH1A1
SCHEMBL15715828 0.93 ALDH1A1 (0.39) L3MBTL1EPAS1GRIN1GRIN2AALDH1A1
SCHEMBL3094274 0.93 ALDH1A1 (0.39) L3MBTL1EPAS1GRIN1GRIN2AALDH1A1
SCHEMBL19211543 0.93 L3MBTL1 (0.39) L3MBTL1NOS2NOS3NOS1MEN1
SCHEMBL12926132 0.93 L3MBTL1 (0.39) L3MBTL1NOS2NOS3NOS1MEN1
SCHEMBL9595528 0.93 L3MBTL1 (0.39) L3MBTL1NOS2NOS3NOS1MEN1
SCHEMBL16763803 0.93 L3MBTL1 (0.39) L3MBTL1NOS2NOS3NOS1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022146115-A1 POLYMER COMPRISING PENTAFLUOROPHENYL ESTER AND ELECTROCHEMICAL BIOSENSOR COMPRISING SAME 주식회사 아이센스 2022-07-07 WO disclosed
US-20200216433-A1 GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2020-07-09 US disclosed
US-10040934-B2 Liquid (meth)acrylic syrup for impregnating a fibrous substrate and method for the production thereof, method for impregnating a fibrous substrate, and composite material produced after polymerisation of said pre-impregnated substrate ARKEMA FRANCE (FR) 2018-08-07 US disclosed
US-9567307-B2 Amination of aryl alcohol derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216433-A1 GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF ACBD3, NR3C1, GRN L3MBTL1 1945/4885EPAS1 4333/4885GRIN1 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.