Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850633 | 0.95 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL1851331 | 0.88 | GPR35 (0.60) | GPR35RXFP1 | |
| SCHEMBL21950401 | 0.82 | CDC7 (0.42) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL30640501 | 0.82 | NPC1 (0.45) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL21874522 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL26621957 | 0.82 | NPC1 (0.45) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL21874488 | 0.82 | KDM4E (0.51) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL31490811 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL31456444 | 0.82 | KMT2A (0.42) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL17204739 | 0.81 | LMNA (0.44) | GPR35MAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |