Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26788859 | 0.85 | CTSV (0.35) | HRH3DRD2DRD3 | |
| SCHEMBL12026463 | 0.83 | HRH3 (0.33) | HRH3DRD2DRD3 | |
| SCHEMBL22251602 | 0.83 | HRH3 (0.33) | HRH3DRD2DRD3 | |
| SCHEMBL16750032 | 0.80 | TAAR1 (0.40) | HRH3DRD2DRD3 | |
| SCHEMBL771695 | 0.78 | DRD2 (0.32) | HRH3DRD2DRD3 | |
| SCHEMBL19939282 | 0.77 | HRH3 (0.38) | HRH3 | |
| SCHEMBL16996995 | 0.77 | NPC1 (0.34) | HRH3DRD2DRD3 | |
| SCHEMBL23425718 | 0.76 | CA12 (0.31) | — | |
| SCHEMBL23132933 | 0.76 | CA12 (0.31) | — | |
| SCHEMBL12920256 | 0.75 | SHBG (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567334-B2 | Quinolone derivatives as fibroblast growth factor receptor inhibitors | PRINCIPIA BIOPHARMA, INC. (US) | 2017-02-14 | — | — | US | disclosed |