Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 8/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219110 | 0.92 | GPR52 (0.51) | GPR52S1PR4S1PR5SCDCES2 | |
| SCHEMBL1851846 | 0.90 | GPR52 (0.45) | GPR52S1PR4S1PR5SCDCES2 | |
| SCHEMBL1850455 | 0.89 | GPR52 (0.49) | GPR52S1PR4S1PR5SCDCES2 | |
| SCHEMBL1850259 | 0.86 | GPR52 (0.61) | GPR52S1PR4S1PR5SCDALDH1A1 | |
| SCHEMBL1861066 | 0.85 | GPR52 (0.64) | GPR52S1PR4S1PR5SCDALDH1A1 | |
| SCHEMBL3204669 | 0.84 | GPR52 (0.49) | GPR52S1PR4S1PR5SCDCES2 | |
| SCHEMBL3198656 | 0.84 | GPR52 (0.49) | GPR52S1PR4S1PR5SCDCES2 | |
| SCHEMBL3198211 | 0.80 | GPR52 (0.70) | GPR52S1PR4S1PR5SCDALDH1A1 | |
| SCHEMBL1852537 | 0.80 | GPR52 (0.45) | GPR52S1PR4S1PR5SCDCES2 | |
| SCHEMBL1850454 | 0.79 | MAPT (0.52) | GPR52ALDH1A1MAPTRAB9ABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |