SCHEMBL18503382

SCHEMBL18503382

Cc1ccc(-c2ccc(CCC3CCC(C)CC3)c(F)c2F)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHKA P35790 1/20 0.33
MAOB P27338 1/20 0.32
CHEK1 O14757 1/20 0.31
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10091262 0.88 RAB9A (0.35) CHKAMAOB
SCHEMBL15381460 0.85 CHKA (0.36) CHKAMAOB
SCHEMBL19195105 0.84 CEL (0.36) MAOB
SCHEMBL19985632 0.83 CTSL (0.30)
SCHEMBL22277595 0.82 MAOB (0.36) CHKAMAOB
SCHEMBL12716562 0.82 OPRL1 (0.32)
SCHEMBL12739791 0.82 OPRL1 (0.32)
SCHEMBL803107 0.80 HTR2A (0.32) MAOB
SCHEMBL30200 0.80 HTR2A (0.32) MAOB
SCHEMBL18503383 0.80 HTR2A (0.39) MAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170045765-A1 LCD DEVICE DIC CORPORATION (JP) 2017-02-16 US disclosed