SCHEMBL18504686

SCHEMBL18504686

CC(C)OC(=O)c1cccc(OCF)c1COc1ccn(O)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.34
POLB P06746 4/20 0.33
KDM4E B2RXH2 4/20 0.33
NPSR1 Q6W5P4 2/20 0.33
GABRA5 P31644 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
NR1H4 Q96RI1 2/20 0.32
PDK2 Q15119 1/20 0.32
CA12 O43570 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA7 P43166 3/20 0.32
CA9 Q16790 3/20 0.32
CA14 Q9ULX7 3/20 0.32
ALDH1A1 P00352 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18500756 0.91 KDM4E (0.35) MAPTLMNANPC1POLBKDM4E
SCHEMBL18504688 0.89 SMN1; SMN2 (0.37) MAPTLMNANPC1POLBKDM4E
SCHEMBL18504693 0.89 IRAK4 (0.36) MAPTLMNANPC1POLBKDM4E
SCHEMBL22563866 0.89 MAPT (0.35) MAPTLMNANPC1POLBKDM4E
SCHEMBL18504977 0.89 LMNA (0.35) MAPTLMNANPC1POLBKDM4E
SCHEMBL18500068 0.88 KMT2A (0.35) MAPTPOLBKDM4ENPSR1ALDH1A1
SCHEMBL18504974 0.88 KCNK3 (0.36) MAPTLMNANPC1POLBKDM4E
SCHEMBL18504666 0.86 TBXAS1 (0.39) LMNAPOLBKDM4ENPSR1GABRA5
SCHEMBL18504215 0.86 NPC1 (0.34) MAPTLMNANPC1POLBKDM4E
SCHEMBL18504968 0.86 MAPT (0.38) MAPTLMNANPC1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed