Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504693 | 0.93 | IRAK4 (0.36) | LMNAMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL18504241 | 0.90 | KLKB1 (0.36) | LMNAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL22564217 | 0.89 | LMNA (0.35) | LMNAMAPTSMN1; SMN2PDE4DNPC1 | |
| SCHEMBL18504686 | 0.89 | MAPT (0.36) | LMNAMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL18504688 | 0.89 | SMN1; SMN2 (0.37) | LMNAMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL18504422 | 0.88 | TBXAS1 (0.38) | LMNAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL18500756 | 0.88 | KDM4E (0.35) | LMNAMAPTNPC1ALDH1A1NPSR1 | |
| SCHEMBL18504974 | 0.87 | KCNK3 (0.36) | LMNAMAPTNPC1NPSR1GABRA5 | |
| SCHEMBL18504924 | 0.86 | TAS2R14 (0.36) | LMNAMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL18504424 | 0.86 | ALDH1A1 (0.40) | LMNASMN1; SMN2ALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |