Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | BLVRB | P30043 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213715 | 0.92 | GPR52 (0.56) | GPR52FOLH1PLA2G2APTGER1AKR1C3 | |
| SCHEMBL1851227 | 0.91 | GPR52 (0.44) | GPR52PTGER1 | |
| SCHEMBL3219164 | 0.91 | GPR52 (0.52) | GPR52PLA2G2A | |
| SCHEMBL1852756 | 0.87 | GPR52 (0.56) | GPR52FOLH1PLA2G2APTGER1RXRA | |
| SCHEMBL3217605 | 0.87 | GPR52 (0.47) | GPR52 | |
| SCHEMBL3209910 | 0.85 | GPR52 (0.69) | GPR52MRGPRX4 | |
| SCHEMBL1848035 | 0.84 | GPR52 (0.53) | GPR52FOLH1PLA2G2AMAOABLVRB | |
| SCHEMBL1851748 | 0.83 | GPR52 (0.44) | GPR52 | |
| SCHEMBL1855888 | 0.83 | GPR52 (0.52) | GPR52FOLH1PLA2G2APTGER1RXRA | |
| SCHEMBL1852762 | 0.82 | GPR52 (0.54) | GPR52PLA2G2APTGER1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885FOLH1 4200/4885PLA2G2A 2173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.