Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.32 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564498 | 0.89 | PDK2 (0.35) | PDK2NPC1MAPTLMNAGABRA5 | |
| SCHEMBL18504947 | 0.88 | RORC (0.38) | MAPTGABRA5KDM4EPOLBKCNK3 | |
| SCHEMBL18504408 | 0.86 | HSD17B10 (0.43) | PDK2NPC1MAPTGABRA5KDM4E | |
| SCHEMBL18504968 | 0.86 | MAPT (0.38) | PDK2NPC1MAPTLMNAGABRA5 | |
| SCHEMBL18504974 | 0.86 | KCNK3 (0.36) | PDK2NPC1MAPTLMNAGABRA5 | |
| SCHEMBL18504684 | 0.85 | PDK2 (0.34) | PDK2NPC1MAPTLMNAGABRA5 | |
| SCHEMBL18504678 | 0.85 | GABRA5 (0.37) | NPC1MAPTLMNAGABRA5KDM4E | |
| SCHEMBL18504604 | 0.85 | GABRA5 (0.39) | GABRA5STIM1ORAI1NR1H4 | |
| SCHEMBL18504400 | 0.84 | ALDH1A1 (0.41) | PDK2MAPTLMNAGABRA5KDM4E | |
| SCHEMBL18504215 | 0.84 | NPC1 (0.34) | PDK2NPC1MAPTLMNAGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |