Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358396 | 0.85 | FTO (0.46) | MAPTNPC1MEN1KMT2AALOX15 | |
| SCHEMBL18240035 | 0.73 | FTO (0.70) | MAPTMEN1KMT2AESR1ALOX15 | |
| SCHEMBL24350868 | 0.73 | PDK2 (0.32) | MAPTMEN1KMT2APDK2GAA | |
| SCHEMBL24942512 | 0.72 | ALDH1A1 (0.33) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24942498 | 0.72 | GAA (0.38) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10169409 | 0.70 | FTO (0.46) | MAPTMEN1KMT2AESR1ALOX15 | |
| SCHEMBL10054989 | 0.69 | FTO (0.58) | MAPTMEN1KMT2AESR1ALOX15 | |
| SCHEMBL24380744 | 0.68 | CYP3A4 (0.33) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL17581044 | 0.66 | FTO (0.57) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL19014826 | 0.65 | FTO (0.46) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027337-A1 | BIOORTHOGONAL REACTION OF AN AMINE N-OXIDE AND A BORON AGENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-16 | — | — | WO | disclosed |