SCHEMBL10169409

SCHEMBL10169409

O=COC1(c2ccccc2)c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 7/20 0.46
HPGD P15428 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 2/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
SMAD3 P84022 1/20 0.46
PRMT1 Q99873 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
BRCA1 P38398 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
HSP90AA1 P07900 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13868038 0.92 FTO (0.49) FTOHPGDMEN1KMT2ATDP1
SCHEMBL14236668 0.86 FTO (0.38) FTOHPGDMEN1KMT2ATDP1
SCHEMBL14236566 0.82 POLB (0.40) MEN1KMT2AMAPTHTTHSD17B10
SCHEMBL12649210 0.82 FTO (0.37) FTOMEN1KMT2ATDP1MAPT
SCHEMBL24358396 0.82 FTO (0.46) FTOHPGDMEN1KMT2ATDP1
SCHEMBL12228681 0.81 SLC6A1 (0.43) MEN1KMT2ACYP2C19CYP2C9ALOX15
SCHEMBL29452872 0.76 FTO (0.50) FTOHPGDMEN1KMT2ATDP1
SCHEMBL14740590 0.76 FTO (0.50) FTOHPGDMEN1KMT2ATDP1
SCHEMBL20468641 0.75 HPGD (0.39) FTOHPGDMEN1KMT2ATDP1
SCHEMBL179720 0.74 FTO (0.49) FTOHPGDMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120116079-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES ELITECHGROUP MDX LLC 2012-05-10 US disclosed
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES ELITECHGROUP MDX LLC 2010-10-14 US disclosed
US-7563618-B2 Oligonucleotide conjugates GERON CORPORATION (US) 2009-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261903-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 FTO 1982/4885HPGD 2517/4885MEN1 1647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.