Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 4/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | MST1R | Q04912 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359602 | 0.85 | ACVR1 (0.31) | ACVR1CLK4MAPK1KITMST1R | |
| SCHEMBL29720572 | 0.85 | ACVR1 (0.31) | ACVR1CLK4MAPK1KITMST1R | |
| SCHEMBL20042377 | 0.84 | RORC (0.34) | ACVR1CLK4MAPK1KITMST1R | |
| SCHEMBL30051769 | 0.84 | RORC (0.34) | ACVR1CLK4MAPK1KITMST1R | |
| SCHEMBL17967734 | 0.81 | DDR1 (0.31) | — | |
| SCHEMBL31534715 | 0.81 | DDR1 (0.31) | — | |
| SCHEMBL20468523 | 0.80 | DGAT1 (0.31) | — | |
| SCHEMBL17941403 | 0.80 | MEN1 (0.33) | CYP2C9AGPAT2RORC | |
| SCHEMBL29521429 | 0.80 | DGAT1 (0.31) | — | |
| SCHEMBL29521944 | 0.80 | MEN1 (0.33) | CYP2C9AGPAT2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523299-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2021-04-14 | — | — | EP | disclosed |
| WO-2018065292-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-12 | — | — | WO | disclosed |