Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24474396 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TP53HPGDSMN1; SMN2 | |
| SCHEMBL27747427 | 0.79 | PLA2G2A (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17395798 | 0.77 | BRD4 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14505829 | 0.76 | KMT2A (0.61) | MEN1KMT2AALDH1A1NPSR1MRGPRX4 | |
| SCHEMBL28767935 | 0.75 | MEN1 (0.70) | MEN1KMT2AMRGPRX4TP53SMN1; SMN2 | |
| SCHEMBL1551997 | 0.75 | TPMT (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5454978 | 0.72 | BRD4 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16749638 | 0.72 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1950244 | 0.72 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21015935 | 0.72 | MRGPRX4 (0.40) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025298-A1 | CROSS-LINKED STAR-SHAPED SELF-ASSEMBLED POLYPEPTIDES AND ITS USE AS CARRIERS IN BIOMEDICAL APPLICATIONS | CENTRO DE INVESTIGACION PRINCIPE FELIPE (ES) | 2017-02-16 | — | — | WO | disclosed |