Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.62 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219552 | 0.90 | GPR52 (0.73) | GPR52MMP13DGAT2AURKAPTGER4 | |
| SCHEMBL1853932 | 0.88 | GPR52 (0.63) | GPR52KLKB1PTGER4KMT2ATP53 | |
| SCHEMBL1850607 | 0.87 | GPR52 (0.52) | GPR52KLKB1PTGER4KMT2ATP53 | |
| SCHEMBL1849604 | 0.87 | GPR52 (0.81) | GPR52PTGER4ALDH1A1CHRM3 | |
| SCHEMBL1850675 | 0.87 | GPR52 (0.69) | GPR52MMP13DGAT2AURKAPTGER4 | |
| SCHEMBL3217756 | 0.87 | GPR52 (0.59) | GPR52MMP13DGAT2AURKAPTGER4 | |
| SCHEMBL1852544 | 0.86 | GPR52 (0.62) | GPR52DGAT2KLKB1PTGER4KMT2A | |
| SCHEMBL1848805 | 0.85 | GPR52 (0.53) | GPR52KLKB1KMT2AROCK2 | |
| SCHEMBL1857499 | 0.84 | GPR52 (0.56) | GPR52MMP13DGAT2AURKAPTGER4 | |
| SCHEMBL1853272 | 0.83 | GPR52 (0.53) | GPR52MMP13DGAT2PTGER4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |