Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.81 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207056 | 0.90 | GPR52 (1.00) | GPR52PTGER4CHRM3ALDH1A1POLB | |
| SCHEMBL1853932 | 0.88 | GPR52 (0.63) | GPR52PTGER4ADORA3 | |
| SCHEMBL1852544 | 0.87 | GPR52 (0.62) | GPR52PTGER4CYP3A4ADORA3CYP1A2 | |
| SCHEMBL1851622 | 0.87 | GPR52 (0.81) | GPR52USP2CYP3A4CHRM3NR1I2 | |
| SCHEMBL1849610 | 0.87 | GPR52 (0.93) | GPR52PTGER4 | |
| SCHEMBL1850671 | 0.87 | GPR52 (0.62) | GPR52PTGER4CHRM3ALDH1A1 | |
| SCHEMBL3206470 | 0.87 | GPR52 (0.81) | GPR52PTGER4CHRM3ALDH1A1POLB | |
| SCHEMBL1851194 | 0.86 | GPR52 (0.70) | GPR52PTGER4ALDH1A1 | |
| SCHEMBL1856279 | 0.84 | GPR52 (0.77) | GPR52PTGER4 | |
| SCHEMBL1851052 | 0.84 | GPR52 (0.58) | GPR52CYP3A4ADORA3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |