Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407441 | 0.91 | KDM4E (0.52) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL15146684 | 0.84 | KDM4E (0.46) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL19426004 | 0.84 | DNM1 (0.50) | PAOXKDM4EMAPK1HIF1AKDM5A | |
| SCHEMBL17393151 | 0.83 | KDM4E (0.44) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL9547380 | 0.83 | KDM4E (0.44) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL12265757 | 0.83 | KDM4E (0.44) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL15473842 | 0.82 | ALDH1A1 (0.43) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL8927622 | 0.81 | PAOX (0.50) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL16317805 | 0.80 | PAOX (0.47) | PAOXKDM4EMAPK1HIF1AMTNR1A | |
| SCHEMBL25817395 | 0.79 | KDM4E (0.58) | PAOXKDM4EMAPK1HIF1AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4173485-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-03 | — | — | EP | disclosed |
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-3130592-A1 | ANALOGUES OF 4H-PYRAZOLO[1,5- ]BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-02-15 | — | — | EP | disclosed |