SCHEMBL18506936

SCHEMBL18506936

O=C(NCCCN1CCC(Cc2ccccc2)CC1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.78
SLC6A4 P31645 6/20 0.78
CCR3 P51677 4/20 0.76
CHRM4 P08173 1/20 0.74
TMEM97 Q5BJF2 6/20 0.72
MEN1 O00255 1/20 0.62
HTT P42858 1/20 0.62
KMT2A Q03164 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29432094 0.85 CHRM4 (1.00) SLC6A2SLC6A4CCR3CHRM4
SCHEMBL17194340 0.85 OPRM1 (0.66) SLC6A2SLC6A4CCR3CHRM4MEN1
SCHEMBL18507035 0.85 CHRM4 (0.65) SLC6A2SLC6A4CCR3CHRM4TMEM97
SCHEMBL18507033 0.84 MCHR2 (0.75) SLC6A2SLC6A4CHRM4HTTSMN1; SMN2
SCHEMBL17194187 0.84 CHRM4 (0.64) SLC6A2SLC6A4CCR3CHRM4TMEM97
SCHEMBL17194307 0.84 CHRM4 (0.64) SLC6A2SLC6A4CCR3CHRM4TMEM97
SCHEMBL14430677 0.83 CHRM4 (0.62) CHRM4SMN1; SMN2
SCHEMBL17194299 0.83 CHRM4 (0.63) SLC6A2SLC6A4CCR3CHRM4TMEM97
SCHEMBL17194188 0.83 L3MBTL3 (0.67) SLC6A2SLC6A4CCR3CHRM4TMEM97
SCHEMBL18502056 0.83 CHRM4 (0.63) SLC6A2SLC6A4CCR3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131890-B1 COMPOUNDS FOR TREATING VIRAL INFECTIONS PASTEUR INSTITUT KOREA (KR) 2019-04-24 EP disclosed
US-9809602-B2 Compounds for treating viral infections INSTITUT PASTEUR KOREA (KR) 2017-11-07 US disclosed
US-20170044181-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS INSTITUT PASTEUR KOREA (KR) 2017-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044181-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS HAVCR2, MAVS, EIF2AK2 SLC6A2 3168/4885SLC6A4 3863/4885CCR3 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.