Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18508300 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL18496294 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL18496296 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL29719399 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL18508189 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL4580624 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HCAR3TDP1HPGD | |
| SCHEMBL29719195 | 0.76 | HCAR3 (0.57) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL18496291 | 0.76 | HCAR3 (0.57) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL18496278 | 0.76 | HCAR3 (0.57) | KDM4EALDH1A1HCAR3TDP1CYP2D6 | |
| SCHEMBL18496289 | 0.76 | HCAR3 (0.57) | KDM4EALDH1A1HCAR3TDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024412-A1 | SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | NEOMED INSTITUTE (CA) | 2017-02-16 | — | — | WO | disclosed |